Compare online
GLP-1 programs.

Five options. The care, the costs,
and a clearer next step.

Updated September 7, 2026How we compare ↗

Our five-program shortlist

Not sure? Answer 4 quick questions →
2

Remedy Meds

For ongoing clinician access and home delivery

  • Unlimited clinician access by video and chat
  • Medication and home delivery included

Medication + care

Compounded semaglutide

$179/first 4 weeks

Introductory price · 4-week supply

Then $299 per 4-week supply.

Compounded tirzepatide

$279/first 4 weeks

Introductory price · 4-week supply

Then $399 per 4-week supply.

Read Remedy Meds overview & pricing

Remedy Meds combines compounded semaglutide and tirzepatide with clinician access and home delivery. It may suit someone who wants ongoing check-ins and a short recurring supply.

Why consider it: Clinician access by video and chat, with medication and delivery in the plan.

The published offer is $179 for the first four-week supply of compounded semaglutide, then $299 per supply. It includes medication, clinician access and shipping. The page describes check-ins every 28 days. This is the published short-plan offer, not an annual-plan equivalent; an annual offer was not shown on the reviewed page. Compounded tirzepatide is $279 for the first four-week supply, then $399, with medication, clinician access and shipping included.

Remedy Meds compounded semaglutide and tirzepatide product pages, checked September 7, 2026.

3

Henry Meds

For a bundled medication subscription

  • Medication and applicable supplies included
  • Provider access and shipping included

Medication + care

Compounded semaglutide

$197/month

12-month plan · $2,364 total

Effective monthly price on the paid-in-full plan.

Tirzepatide injection

Pricing not published

Injectable program

Confirm current options with provider.

Read Henry Meds overview & pricing

Henry Meds offers a subscription that bundles compounded medication with provider access and fulfillment. Its injectable and oral programs have different pricing.

Why consider it: Medication, applicable supplies and shipping within the subscription.

Published terms list compounded injectable semaglutide at $2,364 paid in full for 12 months, equivalent to $197/month. The plan includes medication, provider access, applicable supplies and shipping; supply and dose depend on the program. Current injectable tirzepatide pricing is not listed in the published program terms; confirm available options directly.

Henry Meds Programs terms, checked September 7, 2026.

4

Sesame

For choosing a provider for brand-name care

  • Choose a provider for ongoing care
  • Brand-name treatment and messaging

Medication + care

Wegovy® (semaglutide)

$383/month

12-month care plan + medication

Average includes the two-month medication offer.

Zepbound® (tirzepatide)

$358/month

2.5 mg starter + annual care

Higher doses cost more. Care and medication billed separately.

Read Sesame overview & pricing

Sesame offers provider choice and ongoing telehealth care. Medication is billed separately, so the displayed example adds both charges.

Why consider it: Provider choice, visits and messaging; insurance assistance for medication.

First-year example: annual care at $59/month equivalent ($708), plus eligible Wegovy pen starter pricing of $199 for two months and $349 for ten months. The first-year average is $383/month. Ongoing equivalent is $408/month at these prices. Medication and care are billed separately. Other medications and insurance can change costs. Zepbound (tirzepatide) at the 2.5 mg starter dose is $358/month including the annual care equivalent. Higher doses cost more; this is a starter-dose example, not a year-long treatment quote.

Sesame weight-loss program and offer terms, checked September 7, 2026.

5

Ro

For brand-name care and insurance assistance

  • Insurance and prior-authorization support
  • Ongoing provider messaging and coaching

Medication + care

Wegovy® (semaglutide)

$398/month

12-month care plan + medication

Average includes the two-month medication offer.

Zepbound® (tirzepatide)

$373/month

2.5 mg starter + annual care

Higher doses cost more. Care and medication billed separately.

Read Ro overview & pricing

Ro combines brand-name treatment access with insurance assistance. Its program can appeal to people who want help checking coverage.

Why consider it: Provider messaging and a dedicated insurance concierge.

Selected first-year example: annual care at $74/month equivalent ($888), plus eligible Wegovy pen starter pricing of $199 for two months and $349 for ten months. The first-year average is $398/month. Ongoing equivalent is $423/month at these prices. Medication is billed separately; multi-month medication discounts may reduce this example further. The $39 introductory membership offer is not applied to this annual-plan calculation. Zepbound (tirzepatide) at the 2.5 mg starter dose is $373/month including the annual care equivalent. Higher doses cost more; this is a starter-dose example, not a year-long treatment quote.

Ro pricing page, checked September 7, 2026.

Medication included in every price example. Brand-name and compounded medications are different products. Plan and offer details appear with each program.

Our top pick

SurpassMD

Online assessment, clinician review and medication delivery in one program.

Start assessment

Still deciding?
Start with what matters to you.

Answer four quick questions to see how our top pick fits your priorities.

Our program reviews.

What each program offers, who it may suit, and the details that matter.

01

SurpassMD

Our top pick for online direct-pay care

SurpassMD brings online assessment, independent clinician review and medication fulfillment into one direct-pay program. That makes it a strong starting point if you want to explore care without navigating insurance coverage.

The appeal is the whole program: medication and clinician review in the displayed plan, a clear route to pharmacy fulfillment, and a choice of compounded semaglutide or tirzepatide with different plan durations. Choose the plan that suits you; a clinician determines the appropriate treatment.

Why consider it
Online care and medication together, HSA/FSA eligibility, Klarna and a choice of plan durations.
Keep in mind
The displayed medication is compounded; it is not an FDA-approved brand-name product.
Start assessment
Pricing & offer details

Compounded semaglutide from $114/month*. Compounded tirzepatide from $177/month*.

20% off your first plan paymentVIP20

*Promotional 364-day plan, quoted as rounded 28-day equivalents. Semaglutide: $1,488 first plan, then $1,860 at renewal. Tirzepatide: $2,304 first plan, then $2,880 at renewal.

Shorter plans are also available. VIP20 applies to the first payment only; pricing depends on the selected plan.

Compare semaglutide & tirzepatide
Cash-pay plan examples; offer and billing details appear in each provider card
ProgramSemaglutide + careTirzepatide + careIncludedPlan choiceCare
Remedy Meds$179 /first 4 weeksCompounded semaglutide · medication + care. Introductory price · 4-week supply.$279 /first 4 weeksCompounded tirzepatide. Then $399 per 4-week supply; medication and care included.Medication, clinician access and shipping4-week subscription shownClinician video/chat access and check-ins
Henry Meds$197 /monthCompounded semaglutide · medication + care. 12-month plan · $2,364 total.Ask providerTirzepatide injection. Current injectable pricing is not listed in the published program terms. Ask about available options.Medication, provider access, supplies and shipping12-month plan shown; shorter plans availableOnline provider access and fulfillment
Sesame$383 /monthWegovy® pen + care · first-year example. 12-month care plan + medication.$358 /monthZepbound® (tirzepatide). 2.5 mg starter medication ($299) + annual care ($59/month equivalent). Higher doses cost more.Care membership + medication, separately billedAnnual care plan; medication billed separatelyProvider choice, telehealth visits and messaging
Ro$398 /monthWegovy® pen + care · first-year example. 12-month care plan + medication.$373 /monthZepbound® (tirzepatide). 2.5 mg starter medication ($299) + annual care ($74/month equivalent). Higher doses cost more.Care membership + medication, separately billedAnnual care plan; medication billed separatelyProvider messaging and insurance concierge

Before you
take the next step.

The questions that matter when choosing a program.

What happens when I click through?

You’ll continue to SurpassMD. A licensed clinician reviews your information before any treatment decision. Clicking here does not enroll you or charge you.

Do the prices include medication?

Every example here includes medication and care. For Sesame and Ro, we added the separate care membership and the specified Wegovy pen cash price. The others show bundled compounded semaglutide plans. These examples do not represent every treatment, promotion or insurance scenario.

Do I need insurance for SurpassMD?

No. SurpassMD is a direct-pay program. If you want to explore insurance coverage for brand-name medication, Ro and Sesame also offer assistance; your actual costs depend on your coverage.

How is treatment decided?

An independent licensed clinician reviews your health information and determines whether treatment is appropriate. A prescription is not guaranteed. Compounded medications are not FDA-approved and have not been reviewed by the FDA for safety, effectiveness or quality; they are not the same products as branded Wegovy.

Ready to take the next step?

Begin your online assessment.

Start assessment

How this comparison was prepared

We compared published care options, medication inclusion, plan choices and pricing. Rankings reflect editorial decisions and commercial relationships. The list covers five selected programs; it is not a clinical-quality assessment.

Sources & verification dates

SurpassMD: SurpassMD website, checked September 7, 2026; plan charges verified in the August 30 billing audit. VIP20 confirmed by the program owner.

Remedy Meds: Remedy Meds compounded semaglutide and tirzepatide product pages, checked September 7, 2026.

Henry Meds: Henry Meds Programs terms, checked September 7, 2026.

Sesame: Sesame weight-loss program and offer terms, checked September 7, 2026.

Ro: Ro pricing page, checked September 7, 2026.

Source locations: surpassmd.com; remedymeds.com/medication/comp-sema-inj and /comp-tirz-inj; henrymeds.com/legal/programs; henrymeds.com/landing/weight-management; sesamecare.com/service/online-weight-loss-program; sesamecare.com/medication/semaglutide; ro.co/weight-loss/pricing. Prices and availability can change. Published offers were checked September 7, 2026. Long-plan examples use the stated duration; branded medication examples combine annual care with eligible introductory and ongoing medication prices.